The Seminar Series in Biology presents: “The Mediator Complex and Transcriptional Regulation” presented by Randall Morse

The Seminar Series in Biology presents:
“The Mediator Complex and Transcriptional Regulation” presented by Randall Morse, Research Scientist, Wadsworth Center and Professor, Department of Biomedical Sciences, University at Albany, School of Public Health.

Dr. Morse is a cell and molecular biologist. He has been on the faculty at the University at Albany and the Wadsworth Center since 1993. Since the early 1990s, our laboratory has focused on gene regulation in eukaryotes. Correct regulation of transcription is critical to cell function and development, and deficiencies in this regulation can lead to abnormal development and a variety of genetic diseases, including cancer. We use yeast (Saccharomyces cerevisiae) as a model organism for most of our research. Yeast cells and those of higher eukaryotes, including ours, show strong similarity at the molecular level, and many insights into general transcriptional regulation have emerged from studies with yeast.

In this presentation, Dr. Morse will talk about the Mediator complex, a large, multi-subunit complex that is present in all eukaryotic organisms and plays a critical role in transcription of mRNA. Past and current studies on Mediator structure and function will be discussed, with emphasis on how it is recruited to active genes and what it does at those genes.

This seminar is hosted by the Biology Department and will take place 4 pm Friday October 13 in Science I room 121.

About this seminar series: This series is offered several times throughout the semester to provide our student community with opportunities to learn about scientific research and professions. Speakers may include our own department faculty or students, as well as biologists and other professionals from elsewhere. All are welcome.